HYPER CVAD

C = twice daily Cyclophosphamide (Cytoxan®) DNA-Altering
V = Vincristine (Oncovin®) Blocks Cell Duplication
A = Doxorubicin (Adriamycin®) Rubex® Antitumor Antibiotic
D = Dexamethasone steroidal: anti-inflammatory, Immunosuppressant

 

A fonte é do Wikipedia, está bem simples, mas é o que eu queria ilustrar para vcs.! Quem quiser ver na integra http://en.wikipedia.org/wiki/HyperCVAD

Course A:(O que meus médicos chamam de Ciclo ímpar)

• Cyclophosphamide (Cytoxan) is an alkylating agent given at 300mg/m2 by IV for 3 hours (6 doses) Days 1, 2, and 3
• Vincristine (Oncovin) is a mitotic inhibitor, 2mg IV Days 4 and 11
• Doxorubicin (Adriamycin or Rubex) is an antibiotic with anti-tumour effects, 50mg/m2 IV Day 4
• Dexamethasone is an Immunosuppressant 40mg/day IV or PO Days 1 to 4 Days 11-14
• Cytarabine or Ara-C (Cytosar) is an antimetabolite 70mg IT Day 7
• Mesna (Uromitexan) is a compound used to reduce the incidence of haemorrhagic cystitis, a common side-effect of the administration of cyclophosphamide. It is generally given via intravenous infusion or orally at the same time as cyclophosphamide.
• Methotrexate, an antimetabolite, may be given via the intrathecal route when it is necessary to give chemotherapy which will pass through the blood-brain barrier. 12mg IT Day 2

Course B:(Vulgo Ciclo Par)

• Methotrexate 1000mg/m2 IV over 24 hours Day 1
• Leucovorin 25mg/ m2 IV 24 hours after starting methotrexate infusion Q6H X 6 doses. Leucovorin is used as a 'rescue' agent to prevent excessive cellular damage by methotrexate.
• Sodium bicarbonate 600mg PO (starting day before methotrexate) TID X 4 Days. Sodium bicarbonate is used to produce a mild metabolic alkalosis, desirable when administering large quantities of methotrexate. Urine pH values will be checked to ensure alkalosis prior to the commencement of methotrexate.
• Cytarabine3000mg/m2 IV over 2 hours Q12H X 4 doses Days 2 and 3

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No texto eles citam a via de administração, no meu caso implantaram um cateter subcutaneo que vai ate a minha subclavia. Um ALIVIO…muito melhor que ficar pegando veia periferia, doi muito menos para furar e é muito menos incomodo!

Ai vão umas fotinhas…